Monte-Carlo Diffusion Simulation

Simulation of DNA repair proteins (PARP) migrating to site of nuclear damage The simulation was performed using the outline of a cell nucleus measured using optical microscopy. A region was defined within the code as the site of nuclear damage. Particles moving into this region were considered ‘trapped’.

This was a side project that I carried out with the Luger Lab to develop a simple simulation of particles diffusing within a cell nucleus. This project used masks showing the extent of cell nuclei, then simulated the movement of repair proteins within the nucleus.

Repository

Code and instructions can be found here.