BIO
I am the Biological Image Analysis Group Leader at the BioFrontiers Institute, University of Colorado Boulder. I also run the Bioimaging Lab, a collaborative undergraduate research group, and teach the Quantitative Optical Imaging course at the Departments of Molecular, Cellular, and Developmental Biology and Biochemistry.
My work revolves around creating and utilizing software to extract quantitative data from microscopy datasets. I use advanced microscopes to film living cells over long periods of time. I also develop software to analyze the resulting data and visualize complex datasets.
EDUCATION & EXPERIENCE
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University of Colorado Boulder
BioFrontiers Institute
2024 - PresentBiological Image Analysis Group Leader
- Co-lecturer: Quantitative Optical Imaging
- PI: Bioimaging Lab
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University of Colorado Boulder
BioFrontiers Institute
2016 - 2024Image Analysis Specialist
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University of Colorado
Department of Electrical Engineering
2014 - 2016Postdoctoral Research Associate
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Washington University in St Louis
Department of Biomedical Engineering
2011 - 2014Postdoctoral Research Associate
- Photoacoustic wavefront shaping
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University of Otago
Department of Physics
2007 - 2011PhD
- Optical detection of ultrasound
- Spatial homodyne detection
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University of Otago
Department of Physics
2003 - 2006BSc (Hons I)
- Ion trapping in high-finesse optical traps
RECENT PUBLICATIONS
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The Spatial Distribution of Lipophilic Cations in Gradient Copolymers Regulates Polymer–pDNA Complexation, Polyplex Aggregation, and Intracellular pDNA Delivery
Jessica L. Lawson, Ram Prasad Sekar, Aryelle R. E. Wright, Grant Wheeler, Jillian Yanes, Jordan Estridge, Chelsea G. Johansen, Nikki L. Farnsworth, Praveen Kumar, Jian Wei Tay, and Ramya Kumar.
Biomacromolecules • 2024 -
Poly(l-glutamic acid) augments the transfection performance of lipophilic polycations by overcoming tradeoffs among cytotoxicity, pDNA delivery efficiency, and serum stability
Ram Prasad Sekar, Jessica L. Lawson, Aryelle R. E. Wright, Caleb McGrath, Cesar Schadeck, Praveen Kumar, Jian Wei Tay, Joseph Dragavon, and Ramya Kumar.
RSC Applied Polymers • 2024 -
Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma
Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, and Natalie G. Ahn.
Molecular Biology of the Cell • 2024